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目的 研究肾脏皮质厚度与年龄的关系,确定不同年龄段正常肾脏皮质厚度CT测量的参考范围,筛选出与年龄相关性最好、易于临床应用的测量方法。方法 (1)确定CT测量肾皮质厚度的准确性:选取因肾脏肿瘤而做全肾切除的18例病人的肾脏标本,测量肾脏正常部分的皮质厚度,将测量结果与术前CT影像肾皮质厚度测量的结果行统计学分析,确定差异有无显著性意义;(2)连续选取120例无肾病,无服用肾脏损害药物史,无高血压史病人的腹部CT资料,分为20-40岁、41-60岁、61-80岁3个年龄组,测量每侧肾脏3个层面皮质、实质的厚度和肾脏径线长,统计学分析3个年龄组间差异有无显著性意义及其与年龄的相关性。结果 增强螺旋CT图像测量的肾脏皮质厚度与肾标本测量的皮质厚度差异无显著性意义(t=0.08,P=0.43)。3个年龄组肾脏皮质厚度均数分别为0.73 cm、0.65 cm、0.53 cm,组间差异有极显著性意义(F=93.403,P<0.01)。肾脏皮质、实质厚度与年龄呈负相关,其中相关性最好的指标是皮质厚度(r=-0.78--0.79);60岁以前肾皮质与肾实质厚度比与年龄无相关性。体型对肾脏皮质厚度的影响不明显。男女性别间皮质厚度的差异无显著性意义(P>0.05)。结论 增强螺旋CT能够准确地测量肾脏皮质的厚度,是研究肾脏形态变化的一种敏感的手段。肾皮质厚度随年龄?
Objective To study the relationship between the renal cortical thickness and age, and to determine the reference range of normal renal cortical thickness CT measurement at different ages, and to screen out the most relevant and easy-to-apply clinical measurement methods. Methods (1) To determine the accuracy of CT in the measurement of renal cortical thickness: Kidney specimens from 18 patients who underwent total nephrectomy for kidney tumors were selected to measure the cortical thickness of the normal part of the kidney. The measurement results were compared with the preoperative CT images of the renal cortical thickness The results of the measurement line statistical analysis to determine whether the difference was statistically significant; (2) continuous selection of 120 cases of no kidney disease, no history of renal damage taking drugs, no history of hypertension in patients with abdominal CT data, divided into 20-40 years old, 41-60 years old, 61-80 years old three age groups, measuring each side of the kidneys of the three layers of cortex, the actual thickness and diameter of the kidney line, statistical analysis of the three age groups, the difference was statistically significant and its age Relevance. Results There was no significant difference between the cortical thickness measured by enhanced CT images and the cortical thickness measured by the renal specimens (t = 0.08, P = 0.43). The average thickness of renal cortex in the three age groups was 0.73 cm, 0.65 cm and 0.53 cm, respectively. There was a significant difference between the two groups (F = 93.403, P <0.01). There was a negative correlation between renal cortical thickness and age. The best correlation was cortical thickness (r = -0.78--0.79). There was no correlation between age-related renal cortex and renal parenchyma thickness before age 60 years. Body size on the cortical thickness of the kidney is not obvious. There was no significant difference in cortical thickness between men and women (P> 0.05). Conclusion Enhanced helical CT can accurately measure the thickness of renal cortex, which is a sensitive method to study the morphological changes of the kidney. Renal cortex thickness with age?