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血管内皮细胞在维持血管生理稳态中发挥了重要的作用,其功能障碍是动脉粥样硬化、冠心病、脑卒中、肿瘤等多种重大疾病发生发展的病理基础,调节血管内皮细胞功能是防治上述疾病的主要途径之一。大量研究表明,皂苷类成分可通过改善血管内皮功能达到治疗疾病的目的。综述了近年来报道的皂苷类成分调节血管内皮功能的研究进展,旨在为皂苷类成分作用机制的阐明和相关重大疾病的防治提供一定参考。
Vascular endothelial cells play an important role in the maintenance of vascular physiological homeostasis, and their dysfunction is the pathological basis for the development of many major diseases such as atherosclerosis, coronary heart disease, stroke and cancer. The regulation of the function of vascular endothelial cells is prevention and treatment One of the main ways of the above diseases. Numerous studies have shown that saponins can improve the endothelial function to achieve the purpose of treatment of diseases. This review summarizes the research progress of saponin components regulating vascular endothelial function in recent years and aims to provide some references for the elucidation of the mechanism of action of saponins and the prevention and treatment of related major diseases.