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目的:探讨阿莫西林-舒巴坦与阿莫西林-克拉维酸用于治疗急性细菌性感染患者的细菌学疗效。方法:选取2014年2月—2016年2月间接受治疗的急性细菌性感染患者96例,按治疗药物的不同将其随机分为阿莫西林-舒巴坦组43例和阿莫西林-克拉维酸组53例;阿莫西林-克拉维酸组患者均给予阿莫西林-克拉维酸治疗,阿莫西林-舒巴坦组均给予阿莫西林-舒巴坦治疗;比较两种药物对不同致病菌的敏感率和药敏结果的敏感率。结果:阿莫西林-舒巴坦治疗后的痊愈率为83.72%高于阿莫西林-克拉维酸为73.58%(P>0.05);阿莫西林-舒巴坦对分离致病菌的敏感率(总有效率)高于阿莫西林-克拉维酸(P<0.05)。结论:阿莫西林-舒巴坦具有良好的抗菌活性,对不同致病菌的敏感率和药敏结果的敏感率均优于阿莫西林-克拉维酸,具有良好的细菌学疗效。
Objective: To investigate the bacteriological efficacy of amoxicillin-sulbactam and amoxicillin-clavulanate in the treatment of patients with acute bacterial infection. Methods: A total of 96 patients with acute bacterial infections who were treated between February 2014 and February 2016 were randomly divided into amoxicillin-sulbactam group (43 cases) and amoxicillin-carat 53 patients in the hyaluronic acid group, amoxicillin-clavulanic acid group in the amoxicillin-clavulanic acid group, and amoxicillin-sulbactam group in the amoxicillin-sulbactam group. Sensitivity of different pathogens and susceptibility of susceptibility results. Results: The cure rate of amoxicillin-sulbactam was 83.72% higher than that of amoxicillin-clavulanic acid (73.58%) (P> 0.05). The sensitivity of amoxicillin-sulbactam to isolated pathogens (Total effective rate) was higher than amoxicillin-clavulanic acid (P <0.05). CONCLUSION: Amoxicillin-sulbactam has good antibacterial activity, sensitivity to different pathogenic bacteria and susceptibility to drug susceptibility are better than amoxicillin-clavulanic acid, and has good bacteriological efficacy.