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目的:探论黏液纤维肉瘤(myxofibrosarcoma,MFS)的临床病理学特点及相似病理疾病的鉴别诊断。方法:收集5例MFS患者资料,观察和分析其组织病理学特征。结果:MFS以中老年多见,表现为四肢或躯干无痛渐生长的肿块,组织病理多为黏液背景下瘤细胞密集区中可见薄壁分支弓形血管围绕,免疫组化表达Vimentin。结论:MFS是一种易侵袭复发的纤维软组织肿瘤,需与黏液性的其它良恶性肿瘤鉴别,临床多手术扩大切除为主综合治疗。
Objective: To investigate the clinicopathological features of myxofibrosarcoma (MFS) and the differential diagnosis of similar pathological diseases. Methods: Data of 5 MFS patients were collected and their histopathological features were observed and analyzed. Results: MFS was more common in middle-aged and elderly patients, showing painless and gradual growth of the limbs or trunk. The histopathology was mostly surrounded by thin-walled arched vessels in the dense tumor cells in mucus, and Vimentin was expressed by immunohistochemistry. Conclusions: MFS is a kind of fibro-soft tissue tumor that is easy to attack and recurrence. It needs to be distinguished from other benign and malignant tumors of mucous and multi-operation and extensive excision.