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肝癌在亚洲地区相当多见,发病率有上升趋势。多数患者在确诊时已有门脉癌栓、肝内外转移或伴有严重的肝硬化而失去手术机会。对于不能手术的患者,应用全身化疗、肝动脉结扎或插管化疗等治疗方法,均未取得满意疗效。1979年,日本学者中雄首次将碘化油注入肝动脉,发现其具有导向作用。80年代初,日本熊本大学用聚苯乙烯马来酸新制癌素/碘化油溶液(SMANCS/LPD)动脉注射,证明碘化油导向作用是肯定的。由于这种导向作用,抗癌药在肿瘤局部可长时间保持较
Liver cancer is quite common in Asia, and the incidence rate is on the rise. Most patients have lost portal cancer thrombi, metastases to the liver, or severe cirrhosis at the time of diagnosis. For inoperable patients, the use of systemic chemotherapy, hepatic artery ligation, or intubation chemotherapy did not achieve satisfactory results. In 1979, the Japanese scholar Zhong Xiong injected the iodized oil into the hepatic artery for the first time and found that it had a guiding effect. In the early 1980s, the University of Kumamoto, Japan used an arterial injection of polystyrene maleate/sodium iodide solution (SMANCS/LPD), which proved that the iodized oil guiding effect was positive. Due to this guiding effect, anti-cancer drugs can stay longer in tumors