不论有无内因子缺乏的胃底萎缩性胃炎(AG)常伴有胃底嗜银内分泌细胞增生.这些增生的细胞中大多数系肠嗜铬样(ECL)细胞.近年来由于内镜检查,屡见报道伴或不伴恶性贫血(PA)的胃底AG患者类癌的发病率较前增高.这些类癌多属多中心者,位于胃体或胃底,主要由ECL细胞组成,如ECL瘤.在卓-艾氏综合征中亦有类似的内分泌细胞增生,因此认为其产生机制 Gastric atrophic gastritis (AG), irrespective of the presence or absence of an intrinsic factor, is often accompanied by proliferation of gastric endophile endocrine cells. Most of these proliferating cells are intestinal chromaffin (ECL) cells. In recent years, due to endoscopy, It has been reported that the incidence of carcinoid in gastric fundus AG patients with or without pernicious anemia (PA) is higher than before. These carcinoids are mostly polycentric and located in the corpus or stomach, mainly composed of ECL cells, such as ECL. Tumor. There is also a similar endocrine cell hyperplasia in Zhuo-Egren’s syndrome, so its mechanism is considered