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作者将急性心肌梗塞(AMI)患者随机分组,分别给予溶栓治疗(组Ⅰ)和常规治疗(组Ⅱ),比较两组的梗塞范围、左室功能、病程和死亡率.方法:533例AMI患者胸痛持续20分钟以上,均有相应的心电图表现,而且症状出现后4小时以内分别收入5处冠心监护病房.组Ⅰ269例,组Ⅱ264例.组Ⅰ内除35例外,234例插管成功,作冠状动脉造影.65例梗塞区供血动脉(IRA)畅通.另169例梗塞区供血动脉闭塞者随即注入链激酶(4,000u/min)直到血块消失,总剂量一般不超过250,000u.梗塞区供血动脉残留严重狭窄者试行经皮穿刺冠状动脉腔内成形术,继以抗凝治疗.1984年前152例
The authors randomized patients with acute myocardial infarction (AMI) to thrombolysis (group I) and conventional therapy (group II), and compared infarct size, left ventricular function, duration and mortality in the two groups.Methods: 533 AMI Patients with chest pain continued for more than 20 minutes, have the corresponding ECG performance, and the symptoms appear within 4 hours after the income of 5 coronary care units, group Ⅰ 269 cases, group Ⅱ 264 cases in group Ⅰ except for 35 cases, 234 cases of successful intubation , Coronary angiography 65 cases of infarction area feeding artery (IRA) unblocked.The other 169 cases of infarction area artery occlusion were injected streptokinase (4,000u / min) until the blood clot disappeared, the total dose is generally not more than 250,000u. Infarction Trial of percutaneous transluminal coronary angioplasty in patients with severe residual arterial stenosis, followed by anticoagulant therapy in 1984, 152 cases