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目的探讨降钙素原(PCT)在尿路感染定位中的临床意义。方法用免疫定量法测定114例尿路感染患者及40例健康者的降钙素原(PCT)、C反应蛋白(CRP)。结果上尿路感染组患者血清降钙素原(PCT)水平明显高于下尿路感染患者组(P<0.01),PCT对上尿路感染诊断的敏感性为81.1%,特异性为85.5%,阳性预测值为80.3%,阴性预测值为92.5%,均高于CRP。结论 PCT对尿路感染的定位有临床意义。
Objective To investigate the clinical significance of procalcitonin (PCT) in the localization of urinary tract infection. Methods The levels of procalcitonin (PCT) and C-reactive protein (CRP) in 114 cases of urinary tract infection and 40 healthy controls were determined by immuno-quantitative method. Results The serum procalcitonin (PCT) level in patients with upper urinary tract infection was significantly higher than that in patients with lower urinary tract infection (P <0.01). The sensitivity of PCT to the diagnosis of upper urinary tract infection was 81.1% and the specificity was 85.5% , The positive predictive value was 80.3%, the negative predictive value was 92.5%, all higher than CRP. Conclusion PCT has clinical significance in the localization of urinary tract infection.