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目的探讨Turcot综合征合并肠道Burkitt淋巴瘤的临床病理特征。方法对1例Turcot综合征合并肠道Burkitt淋巴瘤进行光镜观察及免疫组化标记,并结合文献进行分析。结果患者先后行3次手术。第1次手术病理诊断为结肠多发性绒毛管状腺瘤;第2次手术病理诊断为脑间变性星形细胞瘤;第3次手术病理诊断为结肠多发性绒毛管状腺瘤及结肠Burkitt淋巴瘤。结论依靠临床病理特点,Turcot综合征的诊断相对容易,但其合并淋巴瘤十分罕见。二者之间是否存在一定的关系尚需进一步研究。
Objective To investigate the clinicopathological features of Turcot’s syndrome complicated with intestinal Burkitt’s lymphoma. Methods One case of Turcot’s syndrome with intestinal Burkitt’s lymphoma was observed by light microscopy and immunohistochemistry, and analyzed by literature. Results patients have 3 times the line operation. The first surgical pathology was diagnosed as colon multiple villous adenoma; the second surgical pathology was diagnosed as degenerative astrocytoma; the third surgical pathologic diagnosis was multiple colon villous adenoma and colon Burkitt’s lymphoma. Conclusion Depending on the clinicopathological features, the diagnosis of Turcot syndrome is relatively easy, but its combined lymphoma is very rare. Whether there is a certain relationship between the two needs further study.