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目的：探讨IPS e.max Pres 铸瓷全冠修复对牙周组织的影响。方法选择IPS e.max Pres 铸瓷全冠修复患者79例107颗患牙，在修复前和修复后6个月，测定龈沟液(GCF)量，并运用采用酶联免疫吸附试验(ELISA)对龈沟液中基质金属蛋白酶-2(MMP-2)水平进行分析。结果修复后GCF量、MMP-2水平与修复前比较差异无统计学意义(﹥0.05)。结论 IPS e.max Pres 铸瓷全冠对牙周组织无明显影响，是一种生物相容性良好的修复方式。“,”Objective To observe the ef ects of IPS e.max press ceramic crown on the periodontal tissue of the restored teeth. Methods 79 clinical patients (107 anterior teeth)were selected to be placed by IPS e.max press ceramic crown ,and before and 6 months after rehab,the weight of gingival crevicular fluid (GCF)was mensurated and the level of MMP-2 in GCF was checked by way of enzyme-linked immuno sorbent assay,the result was analyzed. Results The weight of GCF,the level of MMP-2 in GCF after rehab had no significantly statistical dif erence with those before rehab(﹥0.05). Conclusion IPS e.max press ceramic crown has no significantly negative influence on gingival health of the restored teeth. And it is a kind of restoration with favorable biocompatibility.