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从绞股蓝(Gynostemma Pentaphyllum[Jhumb]Mak)中提取的总皂甙具有多种药理作用。本试验从生化和病理的角度探讨了绞股蓝总皂甙与齐墩果酸的保肝作用。实验材料大白鼠从上海实验动物中心购买。绞股蓝总皂甙由本所提供,齐墩果酸样品由长沙中药一厂提供,含量98%。方法和结果一、绞股蓝总皂甙对四氯化碳所引起的大白鼠急性肝损伤的治疗作用选用180~220克健康大白鼠,分成四组,每组8只,第一组为正常对照组,第二组为
Total saponins extracted from Gynostemma Pentaphyllum [Jhumb] Mak have various pharmacological effects. This experiment explored the hepatoprotective effects of Gynostemma saponins and oleanolic acid from the perspective of biochemistry and pathology. The experimental material rat was purchased from Shanghai Experimental Animal Center. The total saponin of Gynostemma pentaphylla was provided by the Institute and the sample of oleanolic acid was provided by Changsha No.1 Traditional Chinese Medicine Factory with a content of 98%. Methods and Results I. Therapeutic effects of Gynostemma saponins on carbon tetrachloride-induced acute liver injury in mice 180-220 g healthy rats were used and divided into four groups of 8 rats each. The first group was a normal control group. The second group is