原发性小肠恶性肿瘤是一种少见的胃肠道肿瘤 ,早期诊断极其困难 ,晚期又容易误诊 ,预后多不良。本文总结 1981～ 1998年期间的原发性小肠恶性肿瘤 16例 ,所有病例在手术前均误诊 ,教训深刻。1　临床资料1.1　一般资料　本组 16例 ,男 12例 ,女 4例 ;年龄 39～ 6 5岁。1.2　临床 Primary malignant tumor of the small intestine is a rare gastrointestinal cancer. Early diagnosis is extremely difficult. In the late stage, it is easy to be misdiagnosed and the prognosis is often poor. This article summarizes 16 cases of primary malignant tumors of the small intestine during the period of 1981 to 1998. All cases were misdiagnosed before surgery and their lessons were profound. 1 Clinical data 1.1 General information The group of 16 patients, 12 males and 4 females; aged 39 to 65 years old. 1.2 Clinical