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日本及其他国家的儿科医师普遍认为静脉注射γ-球蛋白(IVGG)治疗对预防川崎病引起心脏并发症是有效的。八十年代初期,日本就开始采用IVGG治疗川崎病以预防其引起冠状动脉瘤及其他的严重冠状动脉损害,其治疗剂量为200mg/kg,疗程为5天。后来报告IVGG治疗川崎病剂量400mg/kg×4～5天比100～200mg/kg×4～5天好。晚近报告一次大剂量2000mg/kgIVGG治疗比400mg/kg×5天更有效。近10年来,日本采用IVGG治疗川崎病的百分率迅速增加(从
Pediatricians in Japan and other countries generally believe that intravenous gamma-globulin (IVGG) treatment is effective in preventing Kawasaki disease-causing heart complications. In the early 1980s, Japan began to treat Kawasaki disease with IVGG to prevent it from causing coronary aneurysms and other serious coronary artery lesions at a dose of 200 mg / kg for 5 days. Later report IVGG treatment Kawasaki disease dose 400mg / kg × 4 ~ 5 days than 100 ~ 200mg / kg × 4 ~ 5 days is good. It has recently been reported that high dose 2000 mg / kg IVGG treatment is more effective than 400 mg / kg x 5 days. In the past 10 years, the percentage of Japanese patients receiving Kawasaki disease treated with IVGG increased rapidly (from