论文部分内容阅读
目的探讨原发性高血压患者微量白蛋白尿与颈动脉粥样硬化的关系。方法根据24h尿蛋白测定结果,将143例患者分为正常白蛋白尿组(NAU)96例,微量蛋白尿组(MAU)47例。应用高频多普勒超生检测颈动脉内膜中层(IMT)及颈动脉粥样斑块,采用logistic回归分析颈动脉IMT增厚的危险因素。结果143例原发性高血压患者微量蛋白尿的阳性率为33%,MAU组颈动脉IMT明显增厚(1.04±0.25),NAU组颈动脉IMT(0.79±0.18),两组相比较有明显的差别。MAU与颈动脉IMT增厚有明显的相关性。结论MAU是高血压患者颈动脉IMT增厚的一个预测指标,可作为颈动脉粥样硬化的早期指标。
Objective To investigate the relationship between microalbuminuria and carotid atherosclerosis in patients with essential hypertension. Methods According to the result of 24h urinary protein, 143 patients were divided into 96 cases of normal albuminuria group (NAU) and 47 cases of microalbuminuria group (MAU). Carotid artery intima-media thickness (IMT) and carotid plaque were detected by high-frequency Doppler ultrasound. Logistic regression was used to analyze the risk factors of carotid IMT thickened. Results The positive rate of microalbuminuria was 143% in 143 patients with essential hypertension, the carotid IMT was significantly thicker in MAU group (1.04 ± 0.25), and the carotid IMT was 0.79 ± 0.18 in NAU group The difference. There was a clear correlation between MAU and carotid IMT thickened. Conclusions MAU is a predictor of carotid IMT thickening in hypertensive patients and may serve as an early marker of carotid atherosclerosis.