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1990年,Yamamoto等首次报道了ABO各等位基因核苷酸序列的差异。随后,Lee和Chang等采用PCR-RFLP方法进行ABO基因型检测。国内也先后报道了运用PCR-RFLP方法检测ABO基因型。本文报道对广东汉族人群ABO基因座的扩增片段限制性长度多态性进行的调查。
In 1990, Yamamoto et al reported for the first time the differences in the nucleotide sequence of each allele of ABO. Subsequently, Lee and Chang et al. Used PCR-RFLP to detect ABO genotypes. China has also reported the use of PCR-RFLP method to detect ABO genotypes. This article reports the investigation of ABL locus restriction fragment length polymorphism in Guangdong Han population.