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目的探讨药剂师参与处方管理对促进医院抗菌药物合理应用的影响。方法选取2014年1—12月揭西县人民医院收治的1364例住院患者作为研究对象,将其按药剂师参与处方管理政策实施前后分为对照组(684例)和研究组(680例),比较两组患者抗菌药物使用原因分布、联用情况及使用疗程。结果研究组患者治疗用药率明显高于对照组,预防用药率和无指证用药率明显低于对照组,差异均有统计学意义(均P<0.05);研究组患者抗菌药物三联及以上联用率明显低于对照组,疗程>4 d的用药率明显低于对照组,差异均有统计学意义(均P<0.05)。结论药剂师参与处方管理政策的实施对促进医院抗菌药物合理使用具有重要作用。
Objective To explore the influence of pharmacist’s participation in prescription management in promoting rational use of antimicrobial agents in hospitals. Methods A total of 1364 inpatients admitted to the People’s Hospital of Jiexi County from January to December 2014 were selected as study subjects. They were divided into control group (684 cases) and study group (680 cases) according to pharmacist’s prescription management policy. Antibiotics were used to compare the two groups of patients with the reasons for the distribution, combined with the use of treatment. Results The study group was significantly higher than the control group, the prophylaxis rate and the non-evidence-based drug use rate were significantly lower than the control group (all P <0.05); the study group of patients with triple antibacterial drugs and above The rate of treatment> 4 d was significantly lower than that of the control group, the difference was statistically significant (both P <0.05). Conclusion The participation of pharmacists in the prescription management policy plays an important role in promoting rational use of antimicrobial agents in hospitals.