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本文采用鲎试验合成基质偶氮显色法检测33例细菌性腹泻患者血浆内毒素值,并以44例正常健康儿童作为对照,检测结果:(1)正常儿童血浆内毒素值(x±s)为37.27±38.49pg/ml;(2)细菌性腹泻患儿血浆内毒素值为257.76±251.8pg/ml,细菌性腹泻急性期内毒素值明显高于对照组(P<0.01);(3)对其中20例患者急性期与恢复期血浆内毒素测定,急性期血浆内毒素值325.5±246.2pg/ml,恢复期血浆内毒素值为54.5±61.83pg/ml,提示恢复期较急性期明显下降(P<0.01);(4)细菌性腹泻有中毒症状组与无中毒症状组血浆内毒素值分别为362.3±276.9pg/ml及170.6±196.3pg/ml(P<0.05)。
In this paper, 鲎 test synthetic azo coloration assay 33 cases of bacterial diarrhea plasma endotoxin values, and 44 normal healthy children as a control, the test results: (1) normal children plasma endotoxin value (x ± s) (37.27 ± 38.49pg / ml); (2) The plasma endotoxin in children with bacterial diarrhea was 257.76 ± 251.8pg / ml, the bacterial endotoxin in the acute stage of bacterial diarrhea was significantly higher than that in the control group (P <0.01) The plasma endotoxin levels in acute and convalescent phase of 20 patients were 325.5 ± 246.2pg / ml in acute phase and 54.5 ± 61.83pg / ml in convalescent phase, which indicated that convalescent phase was significantly lower than acute phase (P <0.01). (4) The plasma endotoxin values of bacterial diarrhea patients with and without symptoms were 362.3 ± 276.9pg / ml and 170.6 ± 196.3pg / ml respectively (P <0.05).