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大量的临床随机试验结果明确地证实了热疗联合化疗已成为癌症治疗的新的有效方法。热疗联合化疗治疗恶性肿瘤,其效果不仅仅是肿瘤细胞的热损伤和化疗引起的损伤作用之和,同时两者之间还有很好的协同作用,即热疗对化疗具有明确的增敏作用,达到提高化疗疗效的目的。本文就肿瘤热化疗的临床应用和基础研究近况作一综述。
A large number of clinical randomized trials clearly confirm that hyperthermia combined with chemotherapy has become a new and effective method of cancer treatment. Hyperthermia combined with chemotherapy for the treatment of malignant tumors, the effect is not only the sum of the thermal damage caused by tumor cells and chemotherapy-induced injury, and there is a good synergy between the two, that hyperthermia has a clear sensitization to chemotherapy Role, to achieve the purpose of improving the efficacy of chemotherapy. This article reviews the clinical application of thermochemotherapy and basic research status.