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目的 :探讨肝脏CT灌注成像的可行性。材料和方法 :5只小型猪 ,分别以 2 5ml/s× 5s ,2 5ml/s× 10s的方式静脉团注 60 %泛影葡胺 ,1张 /s的速度 ,电影方式连续扫描 60s ,通过增强曲线分析肝脏实质、腹主动脉和门静脉的到达峰值时间 (PTT)、上升段斜率和增强峰值。结果 :腹主动脉的PTT、上升段斜率和增强峰值 ,门静脉的增强峰值和PTT ,肝实质的PTT在两种注药方式之间均有显著性差异 ;门静脉和肝实质的上升段斜率 ,肝实质的增强峰值在两种注药方式之间无显著性差异。结论 :肝脏实质和门静脉的上升段斜率是相对稳定的参数 ,是肝脏CT灌注分析的重要指标
Objective: To investigate the feasibility of hepatic CT perfusion imaging. MATERIALS AND METHODS: Five miniature pigs were dosed intravenously with 60% diatrizoate at a rate of 25ml / s × 5s and 25ml / s × 10s respectively for 1 second at a speed of 60 s per film. Enhancement curves were analyzed for liver parenchymal, peak arrival time (PTT) of the abdominal aorta and portal vein, slope of the ascending segment, and peak enhancement. Results: The PTT of the aorta, the slope and peak value of the rising segment, the peak value of the portal vein and PTT, and the PTT of the liver parenchyma were significantly different between the two injection methods. The slope of the portal vein and the area of the liver parenchyma, There was no significant difference between the two injection modes for the substantial enhancement peak. CONCLUSIONS: The slope of the ascending segment of the liver parenchyma and portal vein is a relatively stable parameter and is an important indicator of hepatic CT perfusion analysis