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目的:研究镉对豚鼠肾上腺皮质细胞形态与功能影响的毒作用特点及可能的机制。方法:选用健康雄生豚鼠以45μg/kg和90μg/kg氯化镉腹腔注射染毒,测定血皮质醇、醛固酮及ACTH(放免法)、血清胆固醇(酶联法)、血和组织镉含量(原子吸收法)和一氧化氮(硝酸
Objective: To study the toxic effects and possible mechanisms of cadmium on the morphology and function of adrenocortical cells in guinea pigs. Methods: Healthy guinea pigs were injected intraperitoneally with 45μg / kg cadmium chloride and 90μg / kg cadmium chloride. Plasma cortisol, aldosterone and ACTH (radioimmunoassay), serum cholesterol (enzyme linked immunosorbent assay), blood and tissue cadmium Absorption method) and nitric oxide (nitric acid