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目的探析采用外科手术治疗低级别胶质瘤合并癫痫患者的临床疗效及安全性。方法选取2009年2月-2012年3月间收治的60例低级别胶质瘤且合并有癫痫患者为研究对象,根据术中患者是否进行脑电监测对致癫痫的病灶进行有效处理进行分组,将患者分为治疗组与对照组,对照组患者20例,均进行单纯切除肿瘤手术治疗,治疗组患者40例,在切除肿瘤的同时对致癫痫的病灶进行有效处理。结果治疗组有效率为92.5%,高于对照组的80.0%,差异有统计学意义(P<0.05)。结论采用手术治疗低级别胶质瘤合并癫痫患者过程中应尽可能将肿瘤全部切除,并且配合脑电监测对致癫痫的病灶进行有效处理,此术疗效较满意,值得临床推广应用。
Objective To investigate the clinical efficacy and safety of surgical treatment of low-grade glioma with epilepsy. Methods Sixty low grade gliomas from February 2009 to March 2012 were enrolled in this study. Patients with epilepsy were enrolled in this study. Patients with epilepsy were divided into two groups according to whether the patients underwent EEG monitoring. The patients were divided into the treatment group and the control group, the control group of 20 patients were treated with simple surgical resection of the tumor, the treatment group of 40 patients, in the removal of the tumor at the same time for the treatment of epileptic lesions effectively. Results The effective rate of the treatment group was 92.5%, which was higher than that of the control group (80.0%), the difference was statistically significant (P <0.05). Conclusion Surgical treatment of low-grade gliomas with epilepsy patients should be as complete removal of the tumor as possible, and with the EEG monitoring of epilepsy lesions for effective treatment, the effect of this surgery is more satisfactory, worthy of clinical application.