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拟付交感神经药能引起持续性调节,可能成为头痛,眼痛和诱发近视眼的原因,如不予以矫正,视力可降低到20/200以下。作者用2％毛果云香硷,2％毛果云香硷联合10:1的托平酰胺(Tropicamide),2％Aceclidine对调节的影响进行了比较。 Aceclidine化学名3-乙酰氧基奎奴里啶水杨酸盐(3-Acetoxygiunucline Salicylate),分子量308.34 此药是一种直接作用于运动终板,又有弱抗胆硷酯酶的拟付交感神经药。缩瞳作用稍大于同浓度毛果芸香硷,对调节影响较毛果云香硷小,而降眼压作用二者相同。在溶液状态超过四周不稳定,所以作成扮剂在临用前予以溶解。作者对18个开角型青光眼病人作了试验,病人年令在26—56岁之间。在试验开始前至少停止青光眼治疗三天,全部病例都未用过长效抗胆硷脂酶药。试验开始与结束前均测眼压。屈光检查
Paying for sympathomimetic drugs can cause sustained regulation, may become a headache, eye pain and cause of myopia causes, if not corrected, visual acuity can be reduced to 20/200 or less. The authors compared the effects of 2% pilocarpine, 2% pilocarpine combined with 10: 1 Tropicamide, and 2% Aceclidine on the modulation. Aceclidine Chemical name 3-Acetoxygunucine Salicylate (3-Acetoxygiunucline Salicylate), molecular weight 308.34 This drug is a direct acting on the motor end plate, there are weak anti-cholinesterase to pay the sympathetic nerve medicine. The role of miosis is slightly greater than the concentration of pilocarpine, the regulation of fructose than fructose-base small, while the role of both intraocular pressure drop the same. In the state of the solution more than four weeks is unstable, so make preparations before use to be dissolved. The authors tested 18 patients with open-angle glaucoma, the patient year-round between 26-56 years old. Glaucoma was stopped for at least three days prior to the start of the trial, and no long-acting anticholinergic agents were used in all cases. IOP was measured at the beginning and end of the experiment. Refractive inspection