目的探讨促红细胞生成素治疗慢性肾衰患者贫血的疗效。方法选择透析组30例,非透析组24例,给予rHuEPO150IU/kg/周,分2～3次皮下注射或静脉注射,两组患者疗程均为12周,观察患者治疗期间血常规、肾功能、血压、自觉症状和不良反应。结果与治疗前相比,治疗结束时,两组患者Hb、HCT均显著升高,肾功能无明显变化。结论rHuEPO对治疗慢性肾衰竭透析及非透析患者贫血疗效好,使用安全。 Objective To investigate the therapeutic effect of erythropoietin on anemia in patients with chronic renal failure. Methods Thirty patients in dialysis group and 24 in non-dialysis group were given rHuEPO150IU / kg / week subcutaneously or intravenously in 2 or 3 times. The course of treatment was 12 weeks in both groups. The blood routine, renal function, Blood pressure, symptoms and adverse reactions. Results Compared with those before treatment, Hb and HCT in both groups were significantly increased at the end of treatment, with no significant changes in renal function. Conclusion rHuEPO is effective in the treatment of anemia in dialysis and non-dialysis patients with chronic renal failure and is safe to use.