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近年来葡萄球菌(尤以凝固酶阴性者)在各种感染症中增多。由于β-内酰胺制剂,特别是头孢菌素抗生素类使用的增多,对这类药物的选用也增加。最近从化脓灶及血液中查出耐头孢菌素抗生素类的葡萄球菌的菌株增加,因此对这些感染症的治疗,必须更换其它类药物。因此,从作用机制不同的常用抗生素中选择药物,用表皮葡萄球菌(下简称表葡菌)与金葡菌进行对比,求得各种抗生素的最低抑菌浓度(MIC)。
In recent years, Staphylococcus aureus (especially coagulase negative) increased in a variety of infectious diseases. Due to the increased use of β-lactam preparations, especially cephalosporin antibiotics, the choice of such drugs is also increased. Recently, strains of staphylococci resistant to cephalosporins have been found to have been found in purulent foci and blood. Therefore, other types of drugs must be replaced for the treatment of these infectious diseases. Therefore, from the different mechanism of action of the commonly used antibiotics to select drugs, with Staphylococcus epidermidis (Staphylococcus aureus) and Staphylococcus aureus were compared to obtain the minimum inhibitory concentration (MIC) of various antibiotics.