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很多研究表明口服避孕药中的雌激素和孕激素成分均与患心血管病危险率有关。皮下埋植Norp-lant~R 6枚胶囊,开始每天约释放左旋18甲基炔诺酮(LNG)70μg,一年半后逐渐降到每天释放35μg,有人发现其对血脂浓度有一定影响。本实验研究了Norplant~R埋植物和可释放高于其三倍剂量LNG的包棒埋植物对胆固醇和高密度脂蛋白-胆固醇(HDL-C)的影响。 20名健康妇女被随机分成两组,A组使用6枚包棒,平均年龄29.7岁;B组使用6枚胶囊,平均年龄28.2岁。所有妇女的生殖能力正常,月经规律,在分娩或人工流产后已经有过第一次月经,没有哺乳期的妇女。避孕胶囊Norplant~R是用硅橡胶制作的管状物。内装LNG结晶,两端封闭,每
Many studies have shown that oral contraceptives and estrogen and progesterone components are associated with the risk of cardiovascular disease risk. Subcutaneous implants of Norp-lant ~ R 6 capsules started about daily release of 18-normethionone (LNG) 70μg, a year and a half after gradually reduced to 35μg per day, it was found that it has an impact on serum lipid levels. In this study, we investigated the effects of Norplant-R implants and implants that contained triply higher levels of LNG on cholesterol and high-density lipoprotein-cholesterol (HDL-C). Twenty healthy women were randomly divided into two groups. Group A used six rods, with an average age of 29.7 years. Group B used six capsules with an average age of 28.2 years. All women have normal fertility, regular menstruation, and have had their first menstrual period without breastfeeding after childbirth or abortion. Contraceptive capsules Norplant ~ R is made of silicone rubber tube. Built-LNG crystal, closed at both ends, each