病例介绍男性患者,63岁,因蛋白尿4年、浮肿及四肢无力3年,软瘫1年于1987年9月2日第二次入院。 1983年11月查体发现尿蛋白(++)、偶见红细胞及管型并晨起眼睑浮肿。1985年9月,尿蛋白(++++),眼睑及双下肢浮肿伴双下肢无力、麻木。1986年7月双下肢不能活动,并觉上肢无力麻木。外院查尿酸增高,肌电图示神经元损害。于1986年9月第一次入院。入院查体:全身有米粒大散在的血管痣, Case description Male patients, 63 years old, 4 years due to proteinuria, edema and limb weakness for 3 years, 1 year in soft paralysis on September 2, 1987 second admission. 1983 November urinary albumin examination (++), occasionally erythrocyte and tube type and eyelid edema. September 1985, urinary protein (++++), eyelid and lower extremity edema with weakness of both lower extremities, numbness. July 1986 both lower extremities can not move, and feel upper limb weakness numbness. Outside the hospital check uric acid increased, EMG showed neuronal damage. In September 1986 the first admission. Admission examination: the body has a large grain of nevus scattered,