目的:研究毛叶五味子的化学成分。方法:用反复硅胶柱层析、HPLC和制备TLC进行分离,通过理化性质、光谱数据及与文献报道对照进行结构鉴定。结果:从毛叶五味子的果实中分离得到6个木脂素和1个三萜内酯,分别为:(+)-戈米辛K2(Ⅰ)、戈米辛S(Ⅱ)、前戈米辛(Ⅲ)、五味子酯甲(Ⅳ)、五味子酯乙(Ⅴ)、当归酰基戈米辛Q(Ⅵ)、红花五味子双内酯(Ⅶ)。结论:所有化合物均为首次从该植物中分离得到。 Objective: To study the chemical constituents of Schisandra chinensis. METHODS: The compounds were isolated by repeated silica gel column chromatography, preparative TLC, and physicochemical properties, spectral data, and literature reports. RESULTS: Six lignans and one triterpene lactone were isolated from the fruit of Schisandra sphenanthera, which were (+)-gomycin K2 (I), gomisine S (II), and ex-gomi. Xin (III), schisandrin A (IV), schisandrin B (V), angelica lactoferrin Q (VI), safflower safflower lactone (VII). Conclusion: All compounds were isolated from this plant for the first time.