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目的探讨血脂异常对男性勃起功能的影响。方法于清晨空腹采集外周血标本,测定血清总胆固醇(TC)、总甘油三酯(TG)、高密度脂蛋白(HDL)、低密度脂蛋白(LDL)的浓度。从上述4项结果中至少1项有异常的我院患者中随机选取200例男性患者,4项结果均正常的患者中随机选取200例男性患者,用勃起功能障碍国际指数问卷表(IIEF-5)评估这些患者的勃起功能,分析血脂异常对男性勃起功能的影响。结果血脂异常者勃起功能障碍(ED)的发病率为47%,血脂正常者ED的发病率为30%,两者的发病率差异有统计学意义(P=0.005)。其中,40~59岁人群ED的发病率在两组间有统计学差异。Logistic回归分析发现年龄、HDL、TC/HDL、冠心病、焦虑或抑郁、良性前列腺增生和长期服用影响勃起的药物史与ED的发病有关,除HDL为保护因素,其余均为危险因素。结论高血脂是影响男性勃起功能的一个重要因素,尤其对40~59岁的中年男性的勃起功能影响最明显。HDL水平的下降和TC/HDL比值的上升是ED的重要的危险因素。
Objective To investigate the effect of dyslipidemia on male erectile function. Methods Peripheral blood samples were collected on fasting morning and the levels of total cholesterol (TC), total triglyceride (TG), high density lipoprotein (HDL) and low density lipoprotein (LDL) were measured. A total of 200 male patients were randomly selected from our hospital with at least one of the above four findings. Four of the four patients were selected randomly from 200 male patients and analyzed using the International Index of Erectile Dysfunction (IIEF-5) Questionnaire Evaluate the erectile function of these patients and analyze the effect of dyslipidemia on male erectile function. Results The incidence of erectile dysfunction (ED) was 47% in patients with dyslipidemia and 30% in ED with normal blood lipids, the difference was statistically significant (P = 0.005). Among them, the incidence of ED in 40 to 59-year-olds was statistically different between the two groups. Logistic regression analysis found that age, HDL, TC / HDL, coronary heart disease, anxiety or depression, benign prostatic hyperplasia and long-term use of erectile dysfunction associated with the incidence of ED, in addition to HDL as a protective factor, the rest are risk factors. Conclusion Hyperlipidemia is an important factor affecting male erectile function, especially the erectile function of middle-aged men aged 40-59 years. The decrease of HDL level and the rise of TC / HDL ratio are important risk factors of ED.