极低密度脂蛋白受体(VLDL-R)是低密度脂蛋白受体超家族的成员,主要分布于脂酸代谢活跃的组织,参与甘油三酯的代谢。然而,近年来的研究表明,VLDL-R参与多种细胞的活动,与细胞的增殖、迁移[1]以及细胞的分化等重要细胞功能活动密切相关,故被认为是细胞内重要的多功能受体[2]。人V Very low density lipoprotein receptor (VLDL-R) is a member of the low-density lipoprotein receptor superfamily, mainly distributed in tissues with active fatty acid metabolism, involved in the metabolism of triglycerides. However, recent studies have shown that VLDL-R is involved in a variety of cell activities and is closely related to important cell function activities such as cell proliferation and migration [1] and cell differentiation. Therefore, VLDL-R is considered as an intracellular important multifunctional receptor Body [2]. V