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应用心率功率谱(HRPS)分析26例急性心肌梗塞(AMI)、17例陈旧性心肌梗塞(OMI)及19例健康人的心率变异性(HRV)改变,探讨心肌梗塞后心脏植物神经活性的变化。结果:AMI组与OMI组的高频(HF)及总功率(TP)面积均明显低于对照组,分别为121.94±139.65,124.79±87.67(bpm)2/HzVS644.61±539.09(bpm)2/Hz(P<0.01);818.72±699.42,892.35±573.96(bpm)2/HzVS1864.50±1499.40(bpm)2/Hz(P<O.05);LF/HF比值明显高于对照组(2.03±1.49,1.99±1.32VS0.61±0.26,P<0.01);AMI组与OMI组相比HRPS所有成分无显著性差异。提示心肌梗塞早期就有迷走神经活性降低,交感神经活性相对占优势,这种改变在一定时间内(平均2.1年)不易恢复。
The changes of heart rate variability (HRV) in 26 AMI, 17 AMI and 19 healthy subjects were analyzed by heart rate power spectrum (HRPS) to investigate the changes of cardiac autonomic nerve activity after myocardial infarction . Results: The areas of high frequency (HF) and total power (TP) of AMI group and OMI group were significantly lower than those of the control group (121.94 ± 139.65,124.79 ± 87.67 (bpm) 2 / HzVS644 .61 ± 539.09 (bpm) 2 / Hz (P <0.01); 818.72 ± 699.42,892.35 ± 573.96 (bpm) 2 / HzVS1864.50 ± 1499.40 2 / Hz (P <0.05); LF / HF ratio was significantly higher than that of the control group (2.03 ± 1.49, 1.99 ± 1.32vs0.61 ± 0.26, P <0.01) AMI group and OMI group compared to all components of HRPS no significant difference. Tip early myocardial infarction have decreased vagal activity, sympathetic activity is relatively dominant, this change in a certain period of time (an average of 2.1 years) is not easy to recover.