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为了探讨溶栓治疗对急性心肌梗死(AMI)急性期预后的影响,对我院1989年8月~1997年7月收治的782例急性心肌梗死患者进行分析,其中尿激酶溶栓者297例,未溶栓者485例,对他们住院病死率及有关影响因素作比较分析。结果表明,溶栓组与未溶栓组住院病死率分别为8.4%和11.8%(P>0.05)。但溶性再通组住院病死率(2.5%)明显低于未通组(15.2%)(P<0.01)。合并严重快速心律失常和急性肺水肿的患者,再通组住院病死率明显低于未再通组(P<0.05和P<0.01)。可见冠脉再通对降低住院病死率具有良好作用。
In order to investigate the impact of thrombolytic therapy on acute prognosis of acute myocardial infarction (AMI), 782 patients with acute myocardial infarction admitted to our hospital from August 1989 to July 1997 were analyzed. Among them, 297 cases of urokinase thrombolysis, 485 cases without thrombolysis, their hospital mortality and related factors for comparative analysis. The results showed that the in-hospital mortality rate was 8.4% and 11.8%, respectively (P> 0.05). However, the in-hospital mortality (2.5%) in the recanalization group was significantly lower than that in the unreceded group (15.2%) (P <0.01). In patients with severe tachyarrhythmia and acute pulmonary edema, the in-hospital mortality was significantly lower in the recanalization group than in the non-recanalized group (P <0.05 and P <0.01). Visible coronary recanalization to reduce hospital mortality has a good effect.