论文部分内容阅读
在人类恶性肿瘤中,消化系肿瘤占相当大的比例,并呈不断增加的趋势。新生血管形成很大程度上决定了肿瘤细胞能否转移并导致宿主死亡。血管内皮生长因子(VEGF)是目前发现的活性最强的血管生成因子,可促进内皮细胞增生、迁移及分化,对于实体瘤中新生血管的生成及肿瘤的发展、转移、预后的判断具有十分重要的意义,因而在消化系肿瘤中的研究日渐受到重视。现就VEGF与消化系肿瘤的关系做一综述。
In human malignant tumors, digestive tumors account for a considerable proportion, and showed an increasing trend. Neovascularization largely determines whether tumor cells can metastasize and cause death of the host. Vascular endothelial growth factor (VEGF) is the most active angiogenic factor found at present and can promote the proliferation, migration and differentiation of endothelial cells. It is very important for the neovascularization in solid tumors and the development, metastasis and prognosis of tumors Therefore, the research in the digestive system tumors is getting more and more attention. Now on the relationship between VEGF and gastrointestinal cancer do a review.