铁是多种生命细胞增殖和功能活动的必需元素之一,也是构成微细蛋白(体内携氧物质)和机体能量、物质代谢以及呼吸过程中呼吸链酶的重要成分。低氧是许多疾病所共有的基本病理过程,低氧可抑制呼吸中枢、损害血管内皮细胞,继而导致高原肺水肿、低氧性脑病、运动性贫血等一系列疾病的出现。而铁代谢在这些疾病的发生发展过程中承担了重要作用。因此,研究低氧条件下铁代谢的机制,可以从 Iron is one of the necessary elements for the proliferation and functional activity of many living cells. It is also an important component in the formation of fine proteins (oxygen-carrying substances in the body) and respiratory enzymes in the body’s energy, metabolism, and respiration. Hypoxia is the basic pathological process common to many diseases. Hypoxia can inhibit the respiratory center and damage the vascular endothelial cells, leading to the appearance of a series of diseases such as high altitude pulmonary edema, hypoxic encephalopathy and sports anemia. Iron metabolism plays an important role in the occurrence and development of these diseases. Therefore, the mechanism of iron metabolism under hypoxic conditions can be studied