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鼻息肉的成因尚多不明之处。从组织学看,下鼻甲、中鼻甲内侧粘膜厚而致密,窦口附近粘膜薄而疏松。在淋巴管丰富及高、低组织压交界部,易致炎症渗出物滞留,使粘膜脱出。因反复炎症导致静脉及淋巴管周围炎而妨碍组织液的运送和吸收,向水肿息肉发展。当粘膜发生浸润或水肿使组织压上升时,造成上皮破坏,而水肿浸润组织成为肉芽组织突出,从其周边再生的纤毛上皮覆盖乃成为蒂。息肉中有大小不一内含稠厚粘液的囊泡和腺组织。腺体数量不多,常呈管状,由多列纤毛上皮及位于其间的杯细胞组成,腺的结构与鼻粘膜中的混合腺的泡状管状腺不同。腺体形成的初期,息肉上皮的基底细胞是从分泌细胞和纤毛细胞化生而来,同鼻粘膜的固有腺体不同。来自分泌细胞的粘液因纤毛上皮变性或腺管口阻塞不能排出
The cause of nasal polyps is still unknown. From the histology, the inferior turbinate, the medial turbinate thick and dense mucosa, mucosa near the ostium thin and loose. Rich in the lymphatic vessels and high, low tissue pressure junction, easy to cause inflammation exudate retention, the mucosal prolapse. Due to repeated inflammation leading to venous and lymphatic peripheral inflammation and impede the transport and absorption of tissue fluid to the development of polyps edema. When the mucosa infiltration or edema tissue pressure rise, resulting in epithelial damage, and edema infiltration of tissue into granulation tissue prominent, regenerated from the periphery of the ciliated epithelium covered is to become pedicle. Polyps contain vesicles and glandular tissue that are numerous in size and mucus. Small number of glands, often tubular, by multiple columns of ciliated epithelium and cup cells in between the composition of the glandular structure and nasal mucosa of the mixed gland bubble tubular gland different. In the early stages of glandular formation, the basal cells of the polyp epithelium are derived from the secretory cells and ciliated cells, unlike the natural glands of the nasal mucosa. Secreted cell-derived mucus due to ciliated epithelial degeneration or ductal obstruction can not be discharged