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为探讨盐敏感者在我国少年儿童人群中的分布及其钠代谢改变,261名儿童进行了口服盐水负荷与速尿排销试验相结合的盐敏感性检测,同村测定了红细胞Na+浓度及尿钠排泄量等相关因素。结果:盐敏感儿童检出率21.1%;盐敏感儿童组夜8h尿钠排泄量及其盐负荷后2h尿钠排泄显著低于盐不敏感组(P<0.05及P<0.01)。结论:我国少年儿童人群盐敏感性检出率与国外相近;盐敏感儿童存在钠代谢障碍、钠潴留。
In order to explore the distribution of salt-sensitive children and their sodium metabolism in children and adolescents in our country, 261 children were tested for salt sensitivity by combination of oral saline load and furosemide. In the same village, erythrocyte Na + concentration and urine sodium Excretion and other related factors. Results: The detection rate of salt-sensitive children was 21.1%. Urinary sodium excretion at 8h after salt-sensitive children’s sleep and urinary sodium excretion at 2h after salt-loading were significantly lower than those of salt-sensitive children (P <0.05 and P <0. 01). Conclusion: The detection rate of salt sensitivity of children and adolescents in China is similar to that of foreign countries. Sodium-related disorders and sodium retention are found in salt-sensitive children.