目的分析头孢类抗生素联合利奈唑胺对化脓性脑膜炎的临床效果。方法将收治的160例化脓性脑膜炎患者随机分成两组各80例。单一治疗组单纯用头孢曲松静滴治疗,联合治疗组在单一治疗组基础上联合利奈唑胺治疗。比较两组治疗效果。结果联合治疗组化脓性脑膜炎治疗效果高于单一治疗组,P<0.05;联合治疗组外周血象恢复正常时间、体温正常时间短于单一治疗组,P<0.05;出院时联合治疗组生活质量优于单一治疗组,P<0.05。结论头孢类抗生素联合利奈唑胺对化脓性脑膜炎的临床效果确切,值得推广。 Objective To analyze the clinical effect of cefazolin combined with linezolid on purulent meningitis. Methods 160 patients with purulent meningitis were randomly divided into two groups of 80 cases. The single treatment group was treated with intravenous ceftriaxone only. The combined treatment group was treated with linezolid on the basis of single treatment group. Compare the treatment effect of two groups. Results The therapeutic effect of combined treatment of purulent meningitis was higher than that of the single treatment group, P <0.05; the peripheral blood of the combined treatment group returned to normal time and the normal body temperature was shorter than that of the single treatment group (P <0.05); the quality of life In the single treatment group, P <0.05. Conclusion The clinical effect of cefalosporin combined with linezolid on purulent meningitis is worthy of promotion.