1例51岁男患者,20余年前左足第4趾出现疼痛、间断发作,伴趾部皮肤逐渐变黑;1年前左下肢皮肤多处出现变黑,左足疼痛加重,以“伯格氏病(血管闭塞性血管炎)”收住院。入院查体:左下肢多处皮肤色素沉着,沿大隐静脉走行方向分布;左足背肿胀明显、皮肤发红、皮温升高;第4趾皮肤颜色变黑(图1); A 51-year-old male patient, more than 20 years ago left foot fourth toe pain, intermittent attack, with the toe of the skin gradually darken; a year ago, many left lower extremity skin darkening, left foot pain aggravating to Disease (vascular occlusive vasculitis) "admitted to hospital. Admission examination: multiple left lower extremity skin pigmentation along the direction of the saphenous vein distribution; left dorsal clear swelling, red skin, skin temperature increased; fourth toe skin darkening (Figure 1);