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本文用随机双盲法对44例(治疗组29例,对照组15例)老年收缩期高血压(OSH)患者口服尼群地平(NTP)与安慰剂进行长期(15.66±5.6月)治疗观察。结果:NTP治疗Ⅰ、Ⅱ期OSH有效率为93.1％,其收缩压和舒张压下降幅度均高于对照组,日服NTP5～10mg有55.17％患者获满意疗效,故NTP小剂量、长疗程是OSH较理想的一种药物疗法。
This randomized, double-blind, long-term (15.66 ± 5.6 months) treatment of 44 patients (29 in the treatment group and 15 in the control group) of elderly patients with systolic hypertension (OSH) received oral nitrendipine (NTP) and placebo. Results: The effective rate of OSH in stage I and II of NTP treatment was 93.1%, and the reduction of systolic and diastolic blood pressure was higher than that of the control group. 55.17% of patients on NTP 5 ~ 10 mg had satisfactory curative effect, so the low dose of NTP OSH is a more ideal drug therapy.