论文部分内容阅读
癌基因(Concogene)是一类能诱发恶性肿瘤的DNA(或RNA)顺序,最初是从一些致癌逆转录病毒中发现的。近来通过DNA重组技术发现,在这类病毒宿主如人、鼠和鸡等的正常细胞中都存在着与癌基因的同源序列。经过进一步研究,认为病毒中癌基因(V-onc)可能是过去某个时期从宿主细胞中捕获的。因此把正常细胞中存在癌基因的同源序列叫细胞癌基因(C-onc),它在正常情况下不致癌,并在生长、发育和分化中起着非常重要的作用。但如果在结构、数量和位置上发生某种异常就可能导致正常细胞恶变而引起肿瘤。
Oncogenes (Concogenes) are a class of DNA (or RNA) sequences that can induce malignant tumors and were originally discovered from some oncogenic retroviruses. Recent DNA recombination techniques have revealed that there are homologous sequences with oncogenes in normal cells of such virus hosts such as humans, mice, and chickens. After further research, it is believed that the viral oncogene (V-onc) may have been captured from the host cell in a certain period of time in the past. Therefore, the homologous sequence of oncogenes in normal cells is called the cell oncogene (C-onc), which is not cancerous under normal conditions and plays a very important role in growth, development, and differentiation. However, if something abnormal occurs in the structure, quantity, and position, it may cause normal cells to become malignant and cause tumors.