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[目的]观察益气清热降糖方联合吡格列酮胶囊治疗2型糖尿病疗效。[方法]使用随机平行对照方法,将96例住院及门诊患者按随机数字表法分为两组。对照组48例吡格列酮胶囊,30mg/次,1次/d,口服。心理治疗、饮食治疗、运动治疗、合理应用胰岛素基础治疗。治疗组48例益气清热降糖方(淮山药、黄芪、玉米须、葛根各30g,熟地20g,丹参、麦冬、天花粉各15g,元参、苍术、五味子、黄连各10g)。1剂/d,水煎150mL,早晚口服。西药治疗同对照组。连续治疗30d为1疗程。观测临床症状、血糖水平、炎症因子、不良反应。连续治疗2个疗程,判定疗效。[结果]治疗组痊愈10例,显效18例,有效13例,无效7例,总有效率85.42%。对照组痊愈6例,显效10例,有效14例,无效18例,总有效率62.50%。临床疗效治疗组优于对照组(P<0.05)。血糖水平两组均有改善(P<0.05),治疗组改善优于对照组(P<0.05)。炎症因子两组均有改善(P<0.05),治疗组改善优于对照组(P<0.05)[结论]益气清热降糖方联合吡格列酮胶囊治疗2型糖尿病效果显著,值得推广。
[Objective] To observe the curative effect of Yiqi Qingre Hypoglycemic prescription combined with pioglitazone capsule on type 2 diabetes mellitus. [Methods] Randomized parallel method was used to divide 96 inpatients and outpatients into two groups according to random number table. Control group, 48 cases of pioglitazone capsules, 30mg / time, 1 / d, orally. Psychotherapy, diet therapy, exercise therapy, rational use of insulin based treatment. In the treatment group, 48 cases were treated with Yiqi Qingre Hypoglycemic Formula (Radix Angelicae Sinensis, Radix Astragali, Corn Syrup, Radix Puerariae, 30g, Radix Rehmanniae, Ophiopogon japonicus, 1 / d, decoction 150mL, morning and evening oral. Western medicine treatment with the control group. Continuous treatment of 30d for a course of treatment. Observed clinical symptoms, blood glucose levels, inflammatory factors, adverse reactions. Continuous treatment of 2 courses to determine the efficacy. [Result] In the treatment group, 10 cases were cured, 18 cases were markedly effective, 13 cases were effective and 7 cases were ineffective. The total effective rate was 85.42%. The control group cured 6 cases, markedly effective in 10 cases, effective in 14 cases, 18 cases ineffective, the total effective rate was 62.50%. The clinical efficacy of treatment group than the control group (P <0.05). Blood glucose levels were improved in both groups (P <0.05), the treatment group improved better than the control group (P <0.05). (P <0.05). The treatment group improved more than the control group (P <0.05). [Conclusion] Yiqi Qingre Hypoglycemic combined with pioglitazone capsule has significant effect on type 2 diabetes and is worth promoting.