论文部分内容阅读
应用高效液相色谱技术，对足月正常分娩儿（１１例）、胎儿窘迫儿（３０例）的脐动脉血浆、及足月后羊水（３６例）中儿茶酚胺水平进行测定。结果表明：胎儿窘迫时，儿茶酚胺水平增高，以去甲肾上腺素（ＮＥ）、肾上腺素（Ｅ）为主，其增高的程度与新生儿窒息发生有关，并与Ａｐｇａｒ评分呈负相关。相关系数分别为ｒ＿（ＮＥ）＝－０．６３９（Ｐ＜０．０１），ｒ＿Ｅ＝－０．４５９（Ｐ＜０．０５）。儿茶酚胺增加是胎儿缺氧的早期表现。因此，监测胎儿儿茶酚胺水平，可作为早期诊断胎儿窘迫的一个指标。
The levels of catecholamines in umbilical artery plasma of full-term normal delivery (11 cases), fetal distress (30 cases) and amniotic fluid in full-term (36 cases) were measured by HPLC. The results showed that fetal distress increased catecholamine levels, mainly norepinephrine (NE) and epinephrine (E), which were related to neonatal asphyxia and negatively correlated with Apgar scores. The correlation coefficients were respectively r_ (NE) = -0.639 (P <0.01) and r_E = -0.459 (P <0.05). Increased catecholamines are an early manifestation of fetal hypoxia. Therefore, monitoring fetal catecholamine levels can be used as an early indicator of fetal distress.