目前,种植义齿已在临床上广泛应用,但种植体周围炎可导致种植体-骨界面的丧失、牙槽骨组织吸收、种植体松动等,因此,研究种植体周围炎组织中免疫应答的特征,对于了解种植体周围炎的发病机制有着重要的意义,且对种植体周围炎的诊断和治疗有很大的临床参考价值[1]。笔者以近年来在我院接受牙种植术治疗的30例患者的40枚种植体为观察样本,探讨种植体周围龈沟液(PISF)中基质金属蛋白酶-2(MMP-2)和基质金属蛋酶-9(MMP-9)的表达情况及其与种植体周围炎的关系。报告如下。 At present, implant dentures have been widely used clinically, but peri-implantitis can lead to the loss of implant-bone interface, alveolar bone tissue absorption and loosening of implants. Therefore, the characteristics of immune responses in inflammatory tissues around implants , For understanding the pathogenesis of peri-implantitis is of great significance, and the diagnosis and treatment of peri-implantitis have a great clinical reference value [1]. In this paper, 40 implants of 30 patients who underwent dental implantation in our hospital in recent years were taken as observation samples to investigate the relationship between matrix metalloproteinase-2 (MMP-2) and matrix metal egg (MMP-2) in gingival crevicular fluid The expression of MMP-9 and its relationship with peri-implantitis. The report is as follows.