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目的 探讨术中冰冻病理切片检查误诊的早期甲状腺癌的再治疗方法。方法 回顾性分析35例术中冰冻病理切片检查误诊的早期甲状腺癌患者的临床资料。结果 再次手术行残余甲状腺全切除术 5例 ,患侧残余腺叶并峡部及对侧腺叶部分切除术 2 0例 ,患侧残余腺叶并峡部切除术 6例 ,余 4例未行再次手术。再次手术并发症发生率比首次高。随访期间均无复发或转移。结论 术中冰冻病理切片诊断早期甲状腺癌有较高的假阴性率。对临床上怀疑甲状腺癌的患者可行甲状腺患侧并峡部及对侧部分切除 ,这样可避免再次手术 ,从而降低再次手术并发症的危险。
Objective To investigate the re-treatment of early thyroid cancer misdiagnosed by intraoperative frozen section biopsy. Methods The clinical data of 35 patients with early thyroid cancer who were misdiagnosed as frozen pathological examination were retrospectively analyzed. Results In the reoperation, there were 5 cases of residual thyroidectomy, 20 cases of ipsilateral residual glandular lobes and partial gland lobes resection, 6 cases of ipsilateral residual gland lobes and isthmus resection, and the other 4 cases did not undergo reoperation . The incidence of reoperation was higher than that of the first time. No recurrence or metastasis during follow-up. Conclusion Intraoperative frozen pathological diagnosis of early thyroid cancer has a higher false negative rate. For patients with clinically suspected thyroid cancer feasible thyroid ipsilateral and isthmus and contralateral partial resection, so as to avoid re-surgery, thereby reducing the risk of re-operative complications.