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目的探讨急性冠脉综合症(ACS)与血清中γ-谷氨酰转移酶(GGT)的关系,观察其对ACS患者严重程度的临床预测价值。方法随机选取128名ACS患者,其中不稳定型心绞痛组58例,急性心肌梗死组60例,健康体检者46例作为正常对照组,检测其血清中的GGT、低密度脂蛋白-胆固醇(LDL-C)水平。结果不稳定型心绞痛组、急性心肌梗死组与正常对照组比较GGT、LDL-C水平差异均有统计学意义(P<0.05),两组均高于正常对照组,且急性心肌梗死组GGT与不稳定型心绞痛组差异显著(P<0.01),两组间LDL-C无明显差异。结论 GGT水平与ACS发生密切相关,可反映体内氧化应激能力,预测急性心肌梗死的发生,有助于ACS患者严重程度的评估。
Objective To investigate the relationship between acute coronary syndrome (ACS) and γ-glutamyltransferase (GGT) in serum and to evaluate its clinical value in predicting the severity of ACS. Methods A total of 128 ACS patients were randomly selected. Among them, 58 patients with unstable angina pectoris, 60 acute myocardial infarction patients and 46 healthy volunteers served as normal control group. Serum levels of GGT, LDL- C) level. Results The levels of GGT and LDL-C in patients with unstable angina and acute myocardial infarction were significantly higher than those in normal control group (P <0.05), and both were higher than those in normal control group Unstable angina group difference was significant (P <0.01), LDL-C between the two groups showed no significant difference. Conclusion The level of GGT is closely related to the occurrence of ACS, which can reflect the ability of oxidative stress in vivo and predict the occurrence of acute myocardial infarction. It is helpful to evaluate the severity of ACS.