［背景］探讨和评价经皮钻颅血肿抽吸、溶血引流治疗重症脑出血的方法和治疗效果［病例报 告］ＣＴ定向、手电钻动力驱动下直接经皮钻颅、血肿抽吸、尿激酶溶血引流残血治疗４９例重症脑出血． 结果，有效３４例（６９％），死亡 １５例（３１％）． ［讨论］超早期微创经皮钻颅血肿抽吸、溶血引流治疗脑出 血，损伤小，操作简便，适应症范围宽，疗效好，尤其适应于出血量大的重症脑出血． [Background] To explore and evaluate percutaneous drilling cranial hematoma aspiration, hemolysis and drainage methods of treatment of severe cerebral hemorrhage and treatment effect [case report] CT orientation, hand drill drill directly under the power of percutaneous drilling, hematoma suction, urokinase hemolysis Drainage of residual blood treatment of 49 cases of severe cerebral hemorrhage. Results, effective in 34 cases (69%), 15 cases died (31%). [Discussion] ultra-early minimally invasive percutaneous cranial hematoma aspiration, hemolysis and drainage for the treatment of cerebral hemorrhage, small injury, easy to operate, wide range of indications, good curative effect, especially for heavy bleeding severe bleeding.