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目的探讨剪切波弹性成像(SWE)技术在评估常见病因肝硬化及肝硬化结节中的应用价值。方法确诊为肝硬化代偿期的患者129例,按病因将其分为乙肝后、酒精性和自免性肝硬化组,比较各组及三组两两之间杨氏模量值的差异;根据高频超声判断肝脏有无结节将其分为非结节性和结节性肝硬化组,比较两组间杨氏模量值的差异及病因构成比是否不同。结果乙肝后、自免性和酒精性肝硬化组杨氏模量值依次升高,组间差异有统计学意义(F=54.77,P<0.01),酒精性肝硬化组肝脏杨氏模量值与乙肝后及自免性肝硬化组比较差异均有统计学意义(q=14.79、7.55,P均<0.01),但乙肝后与自免性肝硬化组比较差异无统计学意义(q=2.54,P>0.05)。非结节性与结节性肝硬化组的杨氏模量值差异有统计学意义(t=3.33,P<0.05);且两组病因类型构成比不同,并有统计学意义(2χ=25.49,P<0.005)。结论 SWE技术对评估和鉴别不同原因引起的肝硬化有一定价值,结节性肝硬化组弹性值低于非结节性肝硬化组。
Objective To investigate the value of shear wave elastography (SWE) in assessing the common causes of cirrhosis and cirrhosis. Methods A total of 129 patients with decompensated liver cirrhosis were enrolled in this study. According to their etiological factors, they were divided into two groups according to the cause of hepatitis B, alcoholic and SAH, and the differences in Young ’s modulus between the two groups were compared. According to the high-frequency ultrasound to determine whether the liver nodules will be divided into non-nodular and nodular cirrhosis group, the difference between the two groups Young’s modulus value and the cause of constitutional ratio is different. Results After the hepatitis B, the Young’s modulus value of the patients with SAH and alcoholic cirrhosis increased successively, the difference between the two groups was statistically significant (F = 54.77, P <0.01). The Young’s modulus (Q = 14.79, 7.55, P <0.01), but there was no significant difference between the two groups (q = 2.54 , P> 0.05). There was a significant difference in Young’s modulus between non-nodular and nodular cirrhosis (t = 3.33, P <0.05), and there were significant differences in the constituent ratios between the two groups (2χ = 25.49 , P <0.005). Conclusion The SWE technique has some value in the assessment and identification of cirrhosis caused by different causes. The elasticity of the nodular cirrhosis group is lower than that of the non-nodular cirrhosis group.