论文部分内容阅读
4,5-Dibromo-1-methyl-2-trichloroacetylpyrrole I, prepared by the reaction of 1-me- thyl-2-trichloroacetylpyrrole with Br2 in 98.6 % yield, was condensed with methyl L-2-amino-3- phenylpropanoate to afford methyl 2-(4,5-dibromo-1-methylpyrrole-2-carboxamido)-3-phenylpropa- noate II in 90.8% yield. Crystal data for I: monoclinic system, space group P21/c with a = 8.595(3), b = 10.900(4), c = 12.321(5) ?, a = 92.292(7)°, V = 1153.4(8) ?3, Dc = 2.213 g/cm3, F(000) = 728, C7H4Br2Cl3NO, Mr = 384.28, ? = 0.71073 ?, ì(MoKá) = 7.688 mm–1, Z = 4, R = 0.0338 and wR2 = 0.0840 for 1963 observed reflections with I > 2ó(I). Crystal data for II: monoclinic system, space group P21 with a = 4.886(2), b = 15.921(8), c = 11.635(6) , a = 101.803(9)°, V = 885.9(7) ?3, Dc = 1.665 g/cm3, F(000) = 440, C16H16Br2N2O3, Mr = 444.13, = 0.71073 , ì(MoKá) = 4.590 mm–1, Z = 2, R = 0.0335 and wR2 = 0.0837 for 3191 observed reflections with I > 2ó(I). The crystal structure reveals that compound II forms the one-dimensional chain structure via the intermolecular hydrogen bonds of N(2)HO(1).
4,5-Dibromo-1-methyl-2-trichloroacetylpyrrole I, prepared by the reaction of 1-methyl-2-trichloroacetylpyrrole with Br2 in 98.6% yield, was condensed with methyl L-2-amino-3- phenylpropanoate to For methyl 2- (4,5-dibromo-1 -methylpyrrole-2-carboxamido) -3-phenylpropa- noate II in 90.8% yield. Crystal data for I: monoclinic system, space group P21 / c with a = 8.595 a = 92.292 (7) °, V = 1153.4 (8)? 3, Dc = 2.213 g / cm3, F (000) = 728, C7H4Br2Cl3NO, = 384.28,? = 0.71073 ?, MoKa = 7.688 mm-1, Z = 4, R = 0.0338 and wR2 = 0.0840 for 1963 at reflections with I> 2? (I). Crystal data for II: monoclinic system, Space group P21 with a = 4.886 (2), b = 15.921 (8), c = 11.635 (6), a = 101.803 (9) °, V = 885.9 (000) = 440, C16H16Br2N2O3, Mr = 444.13, = 0.71073, Moha = 4.590 mm -1, Z = 2, R = 0.0335 and wR2 = 0.0837 for 3191 observed reflections with I> 2ó (I) structure reveals that compound II forms th e one-dimensional chain structure via the intermolecular hydrogen bonds of N (2) HO (1).