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目的观察2型糖尿病(T2DM)、慢性阻塞性肺疾病(COPD)及T2DM合并COPD患者的空腹血糖水平,探讨COPD的不同进展阶段对T2DM合并COPD患者空腹血糖的影响。方法 150例入组患者按如下方式进行分组:A组为正常对照组15例;B组为T2DM组15例;C组为COPD组60例,并依照病情严重程度再分为4组,每亚组各15例;D组为T2DM合并COPD组60例,依COPD严重程度分为4组,每亚组各15例。检测患者空腹血糖,比较各组及各亚组之间空腹血糖水平的差异。结果 T2DM合并COPD患者的空腹血糖水平明显高于其他各组(P均<0.05);在4个亚组的比较中,T2DM合并COPD患者空腹血糖水平随COPD严重程度的增高而递增,差异有统计学意义(P<0.05)。结论 T2DM合并COPD的病情进展会影响患者空腹血糖的控制,且空腹血糖水平的升高对COPD预后不利。因此,对合并COPD的T2DM患者,需规范化治疗COPD,控制其病情进展。
Objective To observe the fasting blood glucose level of patients with type 2 diabetes mellitus (T2DM), chronic obstructive pulmonary disease (COPD) and T2DM with COPD and to investigate the effect of different stages of COPD on fasting blood glucose in patients with T2DM complicated with COPD. Methods 150 patients were divided into groups as follows: group A was 15 cases in control group; group B was 15 cases in group T2DM; group C was 60 cases in group COPD and divided into 4 groups according to the severity of illness. Group D was 15 cases in each group. Group D was 60 cases of T2DM with COPD, divided into 4 groups according to the severity of COPD and 15 cases in each subgroup. Fasting blood glucose was measured in patients with different fasting blood glucose levels between groups and subgroups. Results The fasting blood glucose of T2DM patients with COPD was significantly higher than that of other groups (all P <0.05). In the four subgroups, the fasting blood glucose level increased with the severity of COPD in T2DM patients with COPD Significance (P <0.05). Conclusions The progress of T2DM combined with COPD will affect the control of fasting blood glucose in patients with T2DM, and the fasting blood glucose level is unfavorable to the prognosis of COPD. Therefore, COPD patients with T2DM need to standardize the treatment of COPD, to control the progression of the disease.