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目的观察双歧杆菌三联活菌散剂联合曲美布汀治疗功能性便秘的疗效。方法将功能性便秘患者57例随机分为试验组29例及对照组28例。对照组仅使用曲美布汀治疗,试验组使用双歧杆菌三联活菌散剂联合曲美布汀胶囊治疗。对比观察2组临床疗效和治疗后便秘改善情况。结果试验组总有效率为93.1%高于对照组的71.4%(P<0.05)。治疗后2组排便频率、大便性状和其他症状评分均降低,且试验组低于对照组,差异均有统计学意义(P<0.05)。结论双歧杆菌三联活菌散剂联合曲美布汀治疗功能性便秘较单用曲美布汀疗效显著。
Objective To observe the curative effect of Bifidobacterium triple active agent powder and trimebutine on functional constipation. Methods Fifty-seven patients with functional constipation were randomly divided into experimental group (n = 29) and control group (n = 28). The control group was treated with trimebutine alone, and the test group was treated with trimethoprim viable bifidobacterium and trimebutine capsule. The clinical efficacy and constipation improvement in two groups were observed. Results The total effective rate of the experimental group was 93.1% higher than that of the control group (71.4%, P <0.05). The scores of defecation frequency, stool and other symptoms decreased after treatment in both groups, and the experimental group was lower than the control group, the difference was statistically significant (P <0.05). Conclusion Bifidobacterium triple viable powder combined with trimebutine treatment of functional constipation than trimebutine alone effect.