及早完全恢复急性冠脉综合征后心肌血供是每一位心血管内科医生的挑战。然而,即使通过溶栓、血管成形术及冠脉搭桥术等恢复心外膜外血管的血流,也不能完全实现缺血心肌的再灌注。甚至部分患者再灌注之后可能使原有的心肌缺血性损伤进一步加重。其原因为再灌注后微血管损伤引发的心肌无复流现象。本文就无复流现象的病理过程及临床做一综述。 It is a challenge for every cardiovascular physician to early and fully recover the blood supply of the heart after acute coronary syndrome. However, reperfusion of the ischemic myocardium can not be fully achieved even if the blood flow of the epicardial vessels is restored by thrombolysis, angioplasty and coronary artery bypass grafting. Even some patients after reperfusion may make the original myocardial ischemic injury further worsened. The reason is the myocardial no-reflow phenomenon caused by microvascular injury after reperfusion. This article does not review the pathological process of reflux and clinical review.